HTTP Client
1
Total requests
1
HTTP errors
Clients
http_client 1
Requests
| POST | https://api-free.deepl.com/v2/translate | |
|---|---|---|
| Request options | [ "headers" => [ "Authorization" => "DeepL-Auth-Key d1e89e57-c0b5-42df-bbe4-c71dfa4e14b9:fx" ] "json" => [ "text" => [ "AIM: To understand the proportion of uHCC (unresectable hepatocellular carcinoma) patients who achieve successful conversion resection in a high-volume setting with state of the art treatment options.METHODS: We retrospectively reviewed all HCC patients hospitalized to our center from June 1, 2019 to June 1, 2022. Conversion rate, clinicopathological features, response to systemic and/or loco-regional therapy and surgical outcomes were analyzed.RESULTS: A total of 1,904 HCC patients were identified, with 1672 patients receiving anti-HCC treatment. 328 patients were considered up-front resectable. Of the remaining 1344 uHCC patients, 311 received loco-regional treatment, 224 received systemic treatment, and the remainder (809) received combination systemic plus loco-regional treatment. Following treatment, one patient from the systemic group and 25 patients from the combination group were considered to have resectable disease. A high objective\u{A0}response\u{A0}rate (ORR) was observed in these converted patients (42.3% under RECIST v1.1 and 76.9% under mRECIST criteria). The disease control rate (DCR) reached 100%. 23 patients underwent curative hepatectomy. Major post-operative morbidity was equivalent in the both groups (P=0.76). Pathologic complete response (pCR) was 39.1%. During conversion treatment, grade 3 or higher treatment-related adverse events (TRAEs) were observed in 50% of patients. The median follow-up time was 12.9 months (range, 3.9~40.6) from index diagnosis and 11.4 months (range, 0.9~26.9) from resection. Three patients experienced disease recurrence following conversion surgery.CONCLUSIONS: By intensive treatment, a small sub-group of uHCC patients (2%) may potentially be converted to curative resection. Loco-regional combined with systemic modality was relative safe and effective in the conversion therapy. Short-term outcomes are encouraging, but long-term follow-up in a larger patient population are required to fully understand the utility of this approach." ] "source_lang" => "EN" "target_lang" => "FR" ] "timeout" => 20 ] |
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| Response |
456
[ "info" => [ "header_size" => 368 "request_size" => 255 "total_time" => 0.134312 "namelookup_time" => 0.000418 "connect_time" => 0.042111 "pretransfer_time" => 0.089331 "size_upload" => 2066.0 "size_download" => 187.0 "speed_download" => 1395.0 "speed_upload" => 15417.0 "upload_content_length" => 2066.0 "starttransfer_time" => 0.089343 "primary_ip" => "194.124.204.71" "primary_port" => 443 "local_ip" => "185.176.225.12" "local_port" => 48996 "http_version" => 3 "protocol" => 2 "scheme" => "HTTPS" "appconnect_time_us" => 89178 "connect_time_us" => 42111 "namelookup_time_us" => 418 "pretransfer_time_us" => 89331 "starttransfer_time_us" => 89343 "total_time_us" => 134312 "effective_method" => "POST" "start_time" => 1792657953.1411 "original_url" => "https://api-free.deepl.com/v2/translate" "pause_handler" => Closure(float $duration) {#947 : "Symfony\Component\HttpClient\Response\CurlResponse" : { : CurlHandle {#927 …} : Symfony\Component\HttpClient\Internal\CurlClientState {#226 …} : -9223372036854775808 } } "debug" => """ * Trying 194.124.204.71:443...\n * Connected to api-free.deepl.com (194.124.204.71) port 443 (#0)\n * ALPN, offering h2\n * ALPN, offering http/1.1\n * successfully set certificate verify locations:\n * CAfile: /etc/ssl/certs/ca-certificates.crt\n * CApath: /etc/ssl/certs\n * SSL connection using TLSv1.3 / TLS_AES_256_GCM_SHA384\n * ALPN, server accepted to use h2\n * Server certificate:\n * subject: CN=*.deepl.com\n * start date: Sep 20 16:09:30 2026 GMT\n * expire date: Dec 19 16:09:29 2026 GMT\n * subjectAltName: host "api-free.deepl.com" matched cert's "*.deepl.com"\n * issuer: C=US; O=Let's Encrypt; CN=YE1\n * SSL certificate verify ok.\n * Using HTTP2, server supports multi-use\n * Connection state changed (HTTP/2 confirmed)\n * Copying HTTP/2 data in stream buffer to connection buffer after upgrade: len=0\n * Using Stream ID: 1 (easy handle 0x55b47adfab20)\n > POST /v2/translate HTTP/2\r\n Host: api-free.deepl.com\r\n authorization: DeepL-Auth-Key d1e89e57-c0b5-42df-bbe4-c71dfa4e14b9:fx\r\n content-type: application/json\r\n accept: */*\r\n user-agent: Symfony HttpClient (Curl)\r\n accept-encoding: gzip\r\n content-length: 2066\r\n \r\n * We are completely uploaded and fine\n * Connection state changed (MAX_CONCURRENT_STREAMS == 100)!\n < HTTP/2 456 \r\n < content-type: application/json; charset=utf-8\r\n < date: Thu, 22 Oct 2026 08:32:32 GMT\r\n < x-trace-id: 86453dc9d598424c817e272c64663bae\r\n < access-control-expose-headers: Server-Timing, X-Trace-ID\r\n < server-timing: l7_lb_tls;dur=46, l7_lb_idle;dur=0, l7_lb_receive;dur=1, l7_lb_total;dur=50\r\n < strict-transport-security: max-age=63072000; includeSubDomains; preload\r\n < \r\n """ ] "response_headers" => [ "HTTP/2 456 " "content-type: application/json; charset=utf-8" "date: Thu, 22 Oct 2026 08:32:32 GMT" "x-trace-id: 86453dc9d598424c817e272c64663bae" "access-control-expose-headers: Server-Timing, X-Trace-ID" "server-timing: l7_lb_tls;dur=46, l7_lb_idle;dur=0, l7_lb_receive;dur=1, l7_lb_total;dur=50" "strict-transport-security: max-age=63072000; includeSubDomains; preload" ] "response_content" => [ "{"message":"Quota exceeded. You\u0027ve used all the characters included in your free DeepL API plan. To continue translating, upgrade at https://www.deepl.com/your-account/subscription"}" ] ] |
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