Bibliothèque

The Role of High-Intensity Focused Ultrasound as a Local Consolidative Therapy in Multimodal Conversion Treatment for Colorectal Liver Metastases: A Case Series.

IntroductionThis retrospective case series evaluated the feasibility, safety, and potential clinical role of high-intensity focused ultrasound (HIFU) as local consolidative therapy (LCT) in patients w…

Thérapies de Conversion

Du, G., Li, J., Wang, J., Zhang, L., Xu, Y., Yu, N., Li, L., Liu, H., Liu, Q., Song, J., Qiu, W., & Wang, S. (2026). The Role of High-Intensity Focused Ultrasound as a Local Consolidative Therapy in Multimodal Conversion Treatment for Colorectal Liver Metastases: A Case Series.. Technol Cancer Res Treat, 25, 15330338261461451. https://doi.org/10.1177/15330338261461451

01/01/2026 Lire →

TACE plus lenvatinib and envafolimab for conversion therapy in unresectable HCC: a prospective pilot study.

BACKGROUND: Most patients with hepatocellular carcinoma (HCC) are diagnosed at intermediate or advanced stages, when curative resection is not feasible. Conversion therapy aiming to downstage tumors a…

Thérapies de Conversion

Su, Y., Liang, Y., Zhong, D., Chen, Y., Wang, M., Yang, Q., Yan, H., & Huang, X. (2026). TACE plus lenvatinib and envafolimab for conversion therapy in unresectable HCC: a prospective pilot study.. Front Immunol, 17, 1802197. https://doi.org/10.3389/fimmu.2026.1802197

01/01/2026 Lire →

Efficacy of Bronchial Artery Infusion/Chemoembolization Combined with Platinum-Based Chemotherapy and PD-1 Inhibitor in Initially Unresectable Stage III Non-Small Cell Lung Cancer.

BACKGROUND: To evaluate the efficacy of bronchial arterial infusion/bronchial arterial chemoembolization (BAI/BACE) combined with platinum-based doublet chemotherapy and PD-1 inhibitor in patients wit…

Thérapies de Conversion

Quan, X., Lei, L., Chen, X., Jia, X., Wu, C., Ye, B., Huang, Q., Luo, M., Wang, N., Yu, J., & Feng, L. (2026). Efficacy of Bronchial Artery Infusion/Chemoembolization Combined with Platinum-Based Chemotherapy and PD-1 Inhibitor in Initially Unresectable Stage III Non-Small Cell Lung Cancer.. Cancer Manag Res, 18, 589356. https://doi.org/10.2147/CMAR.S589356

01/01/2026 Lire →

Successful conversion therapy of advanced gallbladder carcinoma by chemotherapy combined with immunotherapy: two case reports.

Gallbladder cancer (GBC) is a highly aggressive malignancy of the biliary system and is frequently diagnosed at an advanced stage upon initial presentation. Nonetheless, the introduction of conversion…

Thérapies de Conversion

Li, L., Tong, B., Gong, W., Xu, H., Liao, X., & Sun, H. (2026). Successful conversion therapy of advanced gallbladder carcinoma by chemotherapy combined with immunotherapy: two case reports.. Front Oncol, 16, 1758176. https://doi.org/10.3389/fonc.2026.1758176

01/01/2026 Lire →

Preoperative conversion therapy of camrelizumab combined with paclitaxel and nedaplatin for unresectable advanced esophageal squamous cell carcinoma: a phase 2 study.

BACKGROUND: Patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC) face limited treatment options and poor outcomes. Preclinical evidence supports chemoimmunotherapy as …

Thérapies de Conversion

Zhu, J., Zhang, J., Ling, X., Wang, C., Yang, Y., Xin, Y., Jiang, H., Liang, H., Zhang, L., Qin, X., Lei, J., Fang, C., Yang, X., Wang, Y., Meng, W., Wang, X., Meng, H., & Ma, J. (2025). Preoperative conversion therapy of camrelizumab combined with paclitaxel and nedaplatin for unresectable advanced esophageal squamous cell carcinoma: a phase 2 study.. BMC Med, 24(1), 59. https://doi.org/10.1186/s12916-025-04592-z

28/12/2025 Lire →

Prognostic significance of Albumin-Bilirubin score changes in patients treated with systemic therapy for recurrent hepatocellular carcinoma after liver resection.

PURPOSE: To clarify the characteristics of patients who received systemic therapy for recurrent hepatocellular carcinoma after liver resection and evaluate the associated prognostic factors.METHODS: W…

Thérapies de Conversion

Asahi, Y., Kakisaka, T., Orimo, T., Shimada, S., Nagatsu, A., Aiyama, T., Fujiyoshi, S., Sakamoto, Y., Fujii, Y., Yoshida, Y., Shichi, S., Imaizumi, K., & Taketomi, A. (2025). Prognostic significance of Albumin-Bilirubin score changes in patients treated with systemic therapy for recurrent hepatocellular carcinoma after liver resection.. Surg Today. https://doi.org/10.1007/s00595-025-03217-5

24/12/2025 Lire →

The effectiveness and safety of immune checkpoint inhibitors in conversion or neoadjuvant therapy for hepatocellular carcinoma: a meta-analysis and systematic review.

BACKGROUND: The adoption of immune checkpoint inhibitors in combination with tyrosine kinase inhibitors (TKIs) and/or local therapy, including transarterial chemoembolization (TACE) and hepatic arteri…

Thérapies de Conversion

Hu, L., Xu, Y., Qiao, Y., Wang, A., He, C., & Wang, R. (2025). The effectiveness and safety of immune checkpoint inhibitors in conversion or neoadjuvant therapy for hepatocellular carcinoma: a meta-analysis and systematic review.. BMC Cancer, 26(1), 163. https://doi.org/10.1186/s12885-025-15449-2

23/12/2025 Lire →

Resection versus microwave ablation following conversion therapy for unresectable hepatocellular carcinoma.

BACKGROUND AIMS: Conversion therapy may transform some unresectable hepatocellular carcinomas (uHCCs) into curable ones, but data remained limited comparing subsequent curative-intent treatment option…

Thérapies de Conversion

Jiang, H., Zuo, M., Wei, R., Han, J., Yao, W., Li, W., Fu, Y., Liu, W., Li, C., Lee, S., Ronot, M., Song, B., An, C., & Wu, P. (2025). Resection versus microwave ablation following conversion therapy for unresectable hepatocellular carcinoma.. Int J Surg. https://doi.org/10.1097/JS9.0000000000004486

16/12/2025 Lire →

Advances in the management of ovarian cancer liver metastasis.

Liver metastasis represents a critical challenge in cancer progression, with particularly complex therapeutic implications. In ovarian cancer patients, ovarian cancer liver metastasis (OCLM) marks a d…

Thérapies de Conversion

Li, H., Feng, Y., Wang, Z., & Li, X. (2025). Advances in the management of ovarian cancer liver metastasis.. Int J Cancer, 157(12), 2423-2433. https://doi.org/10.1002/ijc.70065

15/12/2025 Lire →

Clinical Significance of Intratumoral Contrast Pooling on Contrast-Enhanced CT After Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma.

Recent advances in systemic therapies have improved clinical outcomes for patients with unresectable hepatocellular carcinoma (uHCC), as shown in randomized phase 3 clinical trials. Given the availabi…

Thérapies de Conversion

Minamiguchi, K., Irizato, M., Nakano, R., Kunichika, H., Tachiiri, T., Taiji, R., Tsuji, Y., Yasuda, S., Yoshiji, H., Sho, M., & Tanaka, T. (2025). Clinical Significance of Intratumoral Contrast Pooling on Contrast-Enhanced CT After Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma.. Curr Oncol, 32(12). https://doi.org/10.3390/curroncol32120694

09/12/2025 Lire →

Screening HCC Patients Who Can Benefit from the Sequential Treatment of Conversion Therapy and Radical Surgery and Constructing a Predictive Model.

BACKGROUND/OBJECTIVE: This study aimed to develop a new nomogram to predict the likelihood of benefit for patients with advanced HCC who can benefit from the sequential treatment of conversion therapy…

Thérapies de Conversion

Liu, L., Qin, C., Lei, K., Zhang, H., & Zhang, W. (2025). Screening HCC Patients Who Can Benefit from the Sequential Treatment of Conversion Therapy and Radical Surgery and Constructing a Predictive Model.. Cancers (Basel), 17(24). https://doi.org/10.3390/cancers17243928

08/12/2025 Lire →

Safety and efficacy of salvage surgery for unresectable hepatocellular carcinoma after conversion with triple therapy: a systematic review and meta-analysis of data from Chinese patients.

BACKGROUND: Conversion therapy based on vascular intervention combined with targeted immunotherapy has gradually improved treatment outcomes for hepatocellular carcinoma (HCC). Salvage surgery after c…

Thérapies de Conversion

Pang, Q., Mo, X., Tang, Z., Wei, M., Liu, D., Zhou, Z., Huang, B., Bai, T., Wang, X., & Wu, F. (2025). Safety and efficacy of salvage surgery for unresectable hepatocellular carcinoma after conversion with triple therapy: a systematic review and meta-analysis of data from Chinese patients.. World J Surg Oncol, 24(1), 21. https://doi.org/10.1186/s12957-025-04122-4

02/12/2025 Lire →